Untitled Document

This Window Is Draggable, If it is hideing something you wish to see simply Click and hold the left mouse button and move it elsewhere within this browser window.

Commentary 2.

The picture shows spherocytosis of the red cells and there is polychromasia. Some of the cells contain Howell-Jolly bodies. The patient had been splenectomised for hereditary spherocytosis (HS) some years earlier. Mild hereditary spherocytosis is not always easy to recognise microscopically but the abnormality is unlikely in the absence of juvenile erythrocytes in the blood, as evidenced by a raised reticulocyte count or polychromasia. Haemolysis in HS is proportional to the lack of spectrin in the red cell membranes. This deficiency is thought to be due to abnormalities of the protein itself or in some instances to defects in other structural proteins which weaken the binding of spectrin within the membrane skeleton.

If you are having problems you may be using the wrong browser version/type.

Problem 2. Supporting data: A woman aged 41 years, attending an emergency department with minor cuts and abrasions sustained in a fall. She was well prior to the accident and on no medication. Hb = 12.1g/dl, white cells 9.0x10ˆ9/ l, platelets 350 x 10ˆ9 / l. Note what the photomicrograph of this patient's blood film shows and consider your interpretation.